When to pick
Pair it first with Stinger and Spit and test that relationship in the Poison Trickster route. Verify which equipped attacks can actually carry the poison effect.
Read guidePoisonous Saliva
Poisonous Saliva public records: 6. Starting genetic coverage is 1/6, and numeric result coverage is 2/6. The most repeated related routes are Poison Trickster, Endless Extinction, Pressure 20 Complete.
Pair it first with Stinger and Spit and test that relationship in the Poison Trickster route. Verify which equipped attacks can actually carry the poison effect.
Read guideThe links below support specific dated claims, mechanics, or player-route observations on this page; after a patch, use the current in-game text for exact values.
A June Reddit Build Master post records a poison-focused Endless run that reached Extinction 10, where Toxic Sequestration plus Poisonous Saliva and Spit were ticking for about 1100-1500 damage on normal enemies and about 600 on bosses.
Read guideA player who cleared all pressures reports that most wins, including Pressure 20, leaned aggressive, usually toward ability builds that could also go full crab.
Read guideA level 305 Extinction 12 screenshot report with legendary-tier evolution planning, Poisonous Saliva plus Virulent scaling, 3.2M damage, 2112 kills, and 551 POIs.
Read guideA Japanese post-clear note says Pressure 20 stopped rewarding big-body brute force and instead favored Ruminant economy, mushroom XP, poison uptime, terrain adaptation, Wings, and burrow-style final-boss survival.
Read guideA screenshot-backed endless run reached Extinction 5 at level 311 with Body Slam over 7k, poison ticks over 700, 3.8 million damage dealt, 2300+ kills, and 136 POIs.
Read guideA screenshot-backed Pressure 10 clear credits an early Venom Sting pickup, making it a compact poison-route example for players searching Pressure 10 and Sting/Stinger builds.
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