When to pick
Pair it first with Dexterous and Poisonous Saliva and test that relationship in the Poison Trickster route. Cooldown reduction adds uptime, not a survival layer.
Read guideSynapse
Synapse public records: 4. Starting genetic coverage is 2/4, and numeric result coverage is 2/4. The most repeated related routes are Poison Trickster, Pressure 20 Complete, Endless Extinction.
Pair it first with Dexterous and Poisonous Saliva and test that relationship in the Poison Trickster route. Cooldown reduction adds uptime, not a survival layer.
Read guideThe links below support specific dated claims, mechanics, or player-route observations on this page; after a patch, use the current in-game text for exact values.
A recent player report records wins at Pressure 17, 18, and 19 with aggressive builds, including a straight physical-scaling Pressure 19 clear and a Claws plus Spur synergy note.
Read guideA player who cleared all pressures reports that most wins, including Pressure 20, leaned aggressive, usually toward ability builds that could also go full crab.
Read guideA level 305 Extinction 12 screenshot report with legendary-tier evolution planning, Poisonous Saliva plus Virulent scaling, 3.2M damage, 2112 kills, and 551 POIs.
Read guideA Japanese Steam guide for the Zen achievement describes a no-damage and no-hit clear plan on patch 1.0.1 using Vegan, speed, dodge, food efficiency, Nomadic, Pollinator, movement branches, and emergency charm or escape tools.
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